Using clobetasol propionate in the form of a shampoo for the treatment of patients suffering from psoriasis localized in the scalp areaĭirectory of Open Access Journals (Sweden)įull Text Available The study involved 80 adult psoriatic patients with scalp affections at the dermatosis progressing stage. Clobetasol propionate shampoo is efficacious and safe for acute management and long-term maintenance of moderate to severe scalp psoriasis. ![]() There was no greater incidence of skin atrophy, telangiectasia, or hypothalamic-pituitary-adrenal (HPA) axis suppression in the CP shampoo group compared with the vehicle group. After 6 months 31.1% (33/106) of participants in the CP shampoo group were still relapse free versus 8.1% (9/111) of participants in the vehicle group. When relapse occurred (defined as GSS > 2), participants resumed once daily CP shampoo treatment when symptoms diminished (GSS shampoo did not relapse compared with participants treated with vehicle (P shampoo group. ![]() Responders were subsequently randomized to receive the CP shampoo or vehicle twice weekly maintenance regimen for up to 6 months. Participants with moderate to severe scalp psoriasis (global severity score of 3 or 4 on a scale of 0 to 5 ) first received once daily CP shampoo treatment for up to 4 weeks. The aim of this double-blind, randomized, placebo-controlled study was to determine if CP shampoo is suitable for long-term disease control. Poulin, Yves Papp, Kim Bissonnette, Robert Guenther, Lyn Tan, Jerry Lynde, Charles Kerrouche, Nabil Villemagne, HervéĬlobetasol propionate (CP) shampoo 0.05% is an efficacious and safe treatment for scalp psoriasis. The mean (standard deviation) Dermatology Life Quality Index (DLQI) score decreased significantly from 7.0 (4.9) at baseline to 3.2 (3.2) at week 4 (Pshampoo improved the QOL of participants and resulted in high satisfaction.Ĭlobetasol propionate shampoo 0.05% is efficacious and safe for long-term control of scalp psoriasis. Their QOL and degree of satisfaction were evaluated by questionnaires. Participants received once-daily treatment for up to 4 weeks. We evaluated the effect of clobetasol propionate shampoo on QOL and the degree of participant satisfaction with the product. Clobetasol propionate shampoo 0.05% has been shown to be effective and safe for moderate to severe scalp psoriasis. Scalp psoriasis has a considerable impact on the quality of life (QOL) of patients, and most patients are dissatisfied with available treatments. Tan, Jerry Thomas, Richard Wang, Béatrice Gratton, David Vender, Ronald Kerrouche, Nabil Villemagne, Hervé Short-contact clobetasol propionate shampoo 0.05% improves quality of life in patients with scalp psoriasis. Subgroup analyses did not reveal factors predicting treatment outcome, although treatment success tended to be more evident in patients who had received fewer treatments previously. Moreover, the treatment is well-tolerated and efficacious from patients' perspective. Short-contact treatment with clobetasol-17 propionate 0.05% shampoo has high user convenience and patient satisfaction rates. Patient-rated indicators for disease severity improved by 39-46% (P 0.05). Positive treatment satisfaction and user convenience were reported by 66% and 79% of patients respectively. ![]() A total of 41 patients returned both questionnaires (73%). Subgroup analyses were performed to identify variables that may predict treatment outcome. Data on treatment satisfaction, user convenience, safety and effectiveness were assessed on a 7-point Likert scale using postal questionnaires. A total of 56 patients with scalp psoriasis were treated with short-contact clobetasol-17 propionate 0.05% shampoo once daily for 4 weeks. Second, to identify subgroup variables that may predict treatment success or failure. First, to evaluate treatment satisfaction, user convenience safety and effectiveness of clobetasol-17 propionate 0.05% shampoo treatment in daily clinical practice. Safety and clinical effectiveness of clobetasol-17 propionate 0.05% shampoo have been shown in patients with scalp psoriasis. AIM: First, to evaluate treatment satisfaction, user convenience safety and effectiveness of clobetasol-17 propionate 0.05% shampoo treatment in daily clinical Treatment of scalp psoriasis with clobetasol-17 propionate 0.05% shampoo: a study on daily clinical practice.īACKGROUND: Safety and clinical effectiveness of clobetasol-17 propionate 0.05% shampoo have been shown in patients with scalp psoriasis.
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